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The international home of synthetic, physical and biomolecular organic chemistry.
Advance Articles for Organic & Biomolecular Chemistry
First published on the web: 09 February 2010
Asymmetric total synthesis of 1-deoxy-7,8-di-epi-castanospermine
Vincenzo Zambrano, Gloria Rassu, Annamaria Roggio, Luigi Pinna, Franca Zanardi, Claudio Curti, Giovanni Casiraghi and Lucia Battistini,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924721a
First published on the web: 08 February 2010
The UDP-Galp mutase catalyzed isomerization: synthesis and evaluation of 1,4-anhydro-
-D-galactopyranose and its [2.2.2] methylene homologue
Ali Sadeghi-Khomami, Tatiana J. Forcada, Claire Wilson, David A. R. Sanders and Neil R. Thomas,
Org. Biomol. Chem., 2010
DOI: 10.1039/b917409e
Zn(OTf)2-catalyzed addition of amines to carbodiimides: efficient synthesis of guanidines and unpredicted formation of Zn–N amido species
Dongzhen Li, Jie Guang, Wen-Xiong Zhang, Yang Wang and Zhenfeng Xi,
Org. Biomol. Chem., 2010
DOI: 10.1039/b923249b
First published on the web: 05 February 2010
Use of unnatural -peptides as a self-assembling component in functional organic fibres
Elisabeth Torres, Josep Puigmartí-Luis, Ángel Pérez del Pino, Rosa M. Ortuño and David B. Amabilino,
Org. Biomol. Chem., 2010
DOI: 10.1039/b922843h
Non-
-hydroxylated aldehydes with evolved transketolase enzymes
Armando Cázares, James L. Galman, Lydia G. Crago, Mark E. B. Smith, John Strafford, Leonardo Ríos-Solís, Gary J. Lye, Paul A. Dalby and Helen C. Hailes,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924144b
Synthesis of novel 2,5-diarylselenophenes from selenation of 1,4-diarylbutane-1,4-diones or methanol/arylacetylenes
Guoxiong Hua, John B. Henry, Yang Li, Andrew R. Mount, Alexandra M. Z. Slawin and J. Derek Woollins,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924986a
Biosynthesis of the mitochondrial adenine nucleotide translocase (ATPase) inhibitor bongkrekic acid in Burkholderia gladioli
Barbara Rohm, Kirstin Scherlach and Christian Hertweck,
Org. Biomol. Chem., 2010
DOI: 10.1039/b925483h
The thiocarbonyl 
S
is softer than thiolate S: A catalyst-free one-pot synthesis of isothiocyanates in water
Latonglila Jamir, Abdur Rezzak Ali, Harisadhan Ghosh, Francis A. S. Chipem and Bhisma K. Patel,
Org. Biomol. Chem., 2010
DOI: 10.1039/b923336a
First published on the web: 04 February 2010
Design and synthesis of a tetradentate 3-amine-1-carboxylate ligand to mimic the metal binding environment at the non-heme iron(II) oxidase active site
Victoria J. Dungan, Yannick Ortin, Helge Mueller-Bunz and Peter J. Rutledge,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921934j
Preparation of novel alkylated arginine derivatives suitable for click-cycloaddition chemistry and their incorporation into pseudosubstrate- and bisubstrate-based kinase inhibitors
Jeroen van Ameijde, Alex J. Poot, Loek T. M. van Wandelen, Angelique E. M. Wammes, Rob Ruijtenbeek, Dirk T. S. Rijkers and Rob M. J. Liskamp,
Org. Biomol. Chem., 2010
DOI: 10.1039/b922928k
UVA-induced cyclobutane pyrimidine dimers in DNA: a direct photochemical mechanism?
Stéphane Mouret, Coralie Philippe, Jocelyne Gracia-Chantegrel, Akos Banyasz, Szilvia Karpati, Dimitra Markovitsi and Thierry Douki,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924712b
First published on the web: 03 February 2010
A highly selective ratiometric fluorescent probe for 1,4-dithiothreitol (DTT) detection
Baocun Zhu, Xiaoling Zhang, Hongying Jia, Yamin Li, Haipeng Liu and Weihong Tan,
Org. Biomol. Chem., 2010
DOI: 10.1039/b923754b
Asymmetric Si–O coupling of alcohols
Andreas Weickgenannt, Marius Mewald and Martin Oestreich,
Org. Biomol. Chem., 2010
DOI: 10.1039/b925722e
Thiol-dependent DNA cleavage by aminomethylated Beaucage's reagent
Jiahui Zheng, Xiaoqian Liu, Qing Yuan, Yoon-Joo Shin, Daekyu Sun and Yixin Lu,
Org. Biomol. Chem., 2010
DOI: 10.1039/b926217b
First published on the web: 02 February 2010
Highly efficient and stereoselective biosynthesis of (2S,5S)-hexanediol with a dehydrogenase from Saccharomyces cerevisiae
Marion Müller, Michael Katzberg, Martin Bertau and Werner Hummel,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920869k
Formation of 5
,8-cyclo-2-deoxyadenosine in single strand DNA. Theoretical quantum mechanics study
Boleslaw T. Karwowski,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920373g
First published on the web: 01 February 2010
An efficient synthesis of (±)-frondosin B using a Stille–Heck reaction sequence
Kye-Simeon Masters and Bernard L. Flynn,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924542a
Fate of monoterpenes in near-critical water and supercritical alcohols assisted by microwave irradiation
Tony Szuppa, Achim Stolle and Bernd Ondruschka,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924748c
Structurally-variable, rigid and optically-active D2 and D3 macrocycles possessing recognition properties towards C60
Carmine Coluccini, Daniele Dondi, Marco Caricato, Angelo Taglietti, Massimo Boiocchi and Dario Pasini,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920867d
Unravelling the stereoselectivity in 6-exo-trig radical cyclization of 
,
-unsaturated ester-tethered sugars. A tale of two stereocenters
Marcelo T. de Oliveira, Amary C., Daniel H. S. Leal, Maria A. F. Prado, Thais H. Á. da Silva and Ricardo J. Alves,
Org. Biomol. Chem., 2010
DOI: 10.1039/b923414d
Unexpected transalkylation on 3-alkyl-2-alkylthio-1,3,4-thiadiazolium-5-thiolates: A computational and experimental mechanistic study
Arturo Espinosa, Rafaela García, Pedro Molina and Alberto Tárraga,
Org. Biomol. Chem., 2010
DOI: 10.1039/b923243e
On new N-heterocyclic carbene derived alkylidene imidazolines
Christiane E. I. Knappke, Jörg M. Neudörfl and Axel Jacobi von Wangelin,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921655c
First published on the web: 28 January 2010
New family of polyamine macrocycles containing 2,5-diphenyl[1,3,4]oxadiazole as a signaling unit. Synthesis, acid–base and spectrophotometric properties
Gianluca Ambrosi, Mauro Formica, Vieri Fusi, Luca Giorgi, Eleonora Macedi, Mauro Micheloni, Giovanni Piersanti and Roberto Pontellini,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921053a
Reverse-direction (5
3) synthesis of oligonucleotides containing a 3-S-phosphorothiolate linkage and 3-terminal 3-thionucleosides
James W. Gaynor, Michael M. Piperakis, Julie Fisher and Richard Cosstick,
Org. Biomol. Chem., 2010
DOI: 10.1039/b923545k
Searching for intermediates in Prins cyclisations: the 2-oxa-5-adamantyl carbocation
Roger W. Alder, Fabrizio Carta, Christopher A. Reed, Irina Stoyanova and Christine L. Willis,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921957a
Triple molecular target approach to selective melanoma cytotoxicity
Edward B. Skibo, Akmal Jamil, Brittany Austin, Douglas Hansen and Armand Ghodousi,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920260a
Carbo- and heterocyclisation of oxygen- and nitrogen-containing electrophiles by platinum, gold, silver and copper species
Arindam Das, Shariar Md. Abu Sohel and Rai-Shung Liu,
Org. Biomol. Chem., 2010
DOI: 10.1039/b923510h
N-Heterocycle construction via cyclic sulfamidates. Applications in synthesis
John F. Bower, Janjira Rujirawanich and Timothy Gallagher,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921842d
First published on the web: 27 January 2010
A concise synthesis of enantiopure circumdatins E, H and J
Paul E. Zhichkin, Xiaomin Jin, Honglu Zhang, Lisa H. Peterson, Catherine Ramirez, Tara M. Snyder and Hilde S. Burton,
Org. Biomol. Chem., 2010
DOI: 10.1039/b925494c
Complex interactions of pillar[5]arene with paraquats and bis(pyridinium) derivatives
Chunju Li, Qianqian Xu, Jian Li, Feina Yao and Xueshun Jia,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920146g
Hydrogen bonding properties of non-polar solvents
Rafel Cabot, Christopher A. Hunter and Lisa M. Varley,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921003b
Synthesis and fluorescence of the new environment-sensitive fluorophore 6-chloro-2,3-naphthalimide derivative
Alan R. Katritzky, Sevil Ozcan and Ekaterina Todadze,
Org. Biomol. Chem., 2010
DOI: 10.1039/c000684j
First published on the web: 26 January 2010
A flexible asymmetric synthesis of the tetracyclic core of berkelic acid using a Horner–Wadsworth–Emmons/oxa-Michael cascade
Zoe E. Wilson and Margaret A. Brimble,
Org. Biomol. Chem., 2010
DOI: 10.1039/b927219b
First published on the web: 25 January 2010
Synthesis and O-phosphorylation of 3,3,4,4-tetrafluoroaryl-C-nucleoside analogues
Laurent Bonnac, Sarah E. Lee, Guy T. Giuffredi, Lucy M. Elphick, Alexandra A. Anderson, Emma S. Child, David J. Mann and Véronique Gouverneur,
Org. Biomol. Chem., 2010
DOI: 10.1039/b922442d
Molecular recognition of N-protected dipeptides by pseudopeptidic macrocycles: a comparative study of the supramolecular complexes by ESI-MS and NMR
Ignacio Alfonso, Michael Bolte, Miriam Bru, M. Isabel Burguete, Santiago V. Luis and Cristian Vicent,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924981h
First published on the web: 22 January 2010
CO2-induced amidobromination of olefins with bromamine-T
Junpei Hayakawa, Mitsuhiro Kuzuhara and Satoshi Minakata,
Org. Biomol. Chem., 2010
DOI: 10.1039/b923253m
Direct asymmetric aldol reactions between aldehydes and ketones catalyzed by L-tryptophan in the presence of water
Zhaoqin Jiang, Hui Yang, Xiao Han, Jie Luo, Ming Wah Wong and Yixin Lu,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921460g
Biocatalysed concurrent production of enantioenriched compounds through parallel interconnected kinetic asymmetric transformations
Ana Rioz-Martínez, Fabricio R. Bisogno, Cristina Rodríguez, Gonzalo de Gonzalo, Iván Lavandera, Daniel E. Torres Pazmiño, Marco W. Fraaije and Vicente Gotor,
Org. Biomol. Chem., 2010
DOI: 10.1039/b925377g
One-electron oxidation of DNA: thymine versus guanine reactivity
Sriram Kanvah and Gary B. Schuster,
Org. Biomol. Chem., 2010
DOI: 10.1039/b922881k
Micro-scale process development of transaminase catalysed reactions
Matthew D. Truppo and Nicholas J. Turner,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924209k
Exploring neoglycoprotein assembly through native chemical ligation using neoglycopeptide thioesters prepared via NS acyl transfer
Jonathan P. Richardson, Chung-Hei Chan, Javier Blanc, Mona Saadi and Derek Macmillan,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920535g
Drug discovery: phosphinolactone, in vivo bioisostere of the lactol group
Jean-Noël Volle, Damien Filippini, Bartlomiej Krawczy, Nikolay Kaloyanov, Arie Van der Lee, Tangui Maurice, Jean-Luc Pirat and David Virieux,
Org. Biomol. Chem., 2010
DOI: 10.1039/b919345f
First published on the web: 21 January 2010
Replacement of Ala by Aib improves structuration and biological stability in thymine-based -nucleopeptides
Piero Geotti-Bianchini, Alessandro Moretto, Cristina Peggion, Julien Beyrath, Alberto Bianco and Fernando Formaggio,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920211k
Novel thiourea-amine bifunctional catalysts for asymmetric conjugate addition of ketones/aldehydes to nitroalkenes: rational structural combination for high catalytic efficiency
Jia-Rong Chen, Yi-Ju Cao, You-Quan Zou, Fen Tan, Liang Fu, Xiao-Yu Zhu and Wen-Jing Xiao,
Org. Biomol. Chem., 2010
DOI: 10.1039/b925962g
Chemoenzymatic synthesis of the carbasugars carba--L-galactopyranose, carba--L-talopyranose and carba--L-talopyranose from methyl benzoate
Derek R. Boyd, Narain D. Sharma, Nigel I. Bowers, Gerard B. Coen, John F. Malone, Colin R. O'Dowd, Paul J. Stevenson and Christopher C. R. Allen,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921545j
A combined spin trapping/EPR/mass spectrometry approach to study the formation of a cyclic peroxide by dienolic precursor autoxidation
Mathilde Triquigneaux, Laurence Charles, Christiane André-Barrès and Béatrice Tuccio,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921694d
First published on the web: 20 January 2010
Brønsted acid-catalyzed efficient Strecker reaction of ketones, amines and trimethylsilyl cyanide
Guang-Wu Zhang, Dong-Hua Zheng, Jing Nie, Teng Wang and Jun-An Ma,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924272d
Synthesis and biological applications of collagen-model triple-helical peptides
Gregg B. Fields,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920670a
First published on the web: 19 January 2010
Tether influence on the binding properties of tRNALys3 ligands designed by a fragment-based approach
Roba Moumné, Valéry Larue, Bili Seijo, Thomas Lecourt, Laurent Micouin and Carine Tisné,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921232a
Functionalized alkoxy arene diazonium salts from paracetamol
Bernd Schmidt, René Berger and Frank Hölter,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924619c
A coumarin–thiourea conjugate as a fluorescent probe for Hg(II) in aqueous media with a broad pH range 2–12
Yasuhiro Shiraishi, Shigehiro Sumiya and Takayuki Hirai,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924015b
First published on the web: 18 January 2010
Photoinduced DNA cleavage by formation of ROS from oxygen with a neurotransmitter and aromatic amino acids
Tomonori Kawashima, Kei Ohkubo and Shunichi Fukuzumi,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924560j
Kinetics and regioselectivity in the Diels–Alder reaction of fulleroids vs. methanofullerene and C60
Naohiko Ikuma, Yasunori Susami and Takumi Oshima,
Org. Biomol. Chem., 2010
DOI: 10.1039/b918005b
Optoelectronically mismatched oligophenylethynyl-naphthalenediimide SHJ architectures
Santanu Maity, Rajesh Bhosale, Natalie Banerji, Eric Vauthey, Naomi Sakai and Stefan Matile,
Org. Biomol. Chem., 2010
DOI: 10.1039/b917188f
First published on the web: 15 January 2010
Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA
Satu Ikonen, Hana Mací
ková-Cahová, Radek Pohl, Miloslav 
anda and Michal Hocek,
Org. Biomol. Chem., 2010
DOI: 10.1039/b924072a
Computational calculations in microwave-assisted organic synthesis (MAOS). Application to cycloaddition reactions
A. de Cózar, M. C. Millán, C. Cebrián, P. Prieto, A. Díaz-Ortiz, A. de la Hoz and F. P. Cossío,
Org. Biomol. Chem., 2010
DOI: 10.1039/b922730j
Organic co-solvents in aqueous DNA-based asymmetric catalysis
Rik P. Megens and Gerard Roelfes,
Org. Biomol. Chem., 2010
DOI: 10.1039/b921385f
First published on the web: 14 January 2010
Synthesis of phalluside-1 and Sch II using 1,2-metallate rearrangements
Fiona J. Black and Philip J. Kocienski,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920285d
Versatile chiroptics of peptide-induced assemblies of metalloporphyrins
Hirokuni Jintoku, Takashi Sagawa, Tsuyoshi Sawada, Makoto Takafuji and Hirotaka Ihara,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920058d
A new facile synthesis of 3-amidoindole derivatives and their evaluation as potential GSK-3 inhibitors
Anahit Pews-Davtyan, Annegret Tillack, Anne-Caroline Schmöle, Stefanie Ortinau, Moritz J. Frech, Arndt Rolfs and Matthias Beller,
Org. Biomol. Chem., 2010
DOI: 10.1039/b920861e
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