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Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.




Emerging Area

Org. Biomol. Chem., 2006, 4, 4041 - 4047, DOI: 10.1039/b611094k


-Chelation-directed C–H functionalizations using Pd(II) and Cu(II) catalysts: regioselectivity, stereoselectivity and catalytic turnover

Jin-Quan Yu, Ramesh Giri and Xiao Chen


Recent progress in -chelation directed C–H functionalization from the authors' group is described to illustrate the challenges and opportunities in the development of synthetically-useful catalytic reactions involving C–H activation as the key step. Emphasis is placed on strategies for developing catalysis under mild conditions and controlling regio- and stereoselectivity.

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