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Emerging Area
Org. Biomol. Chem., 2008, 6, 4083 - 4088, DOI: 10.1039/b813246a
Mechanistic approaches to palladium-catalyzed alkene difunctionalization reactions
Katrina H. Jensen and Matthew S. Sigman
Alkene difunctionalization, the addition of two functional groups across a double bond, exemplifies a class of reactions with significant synthetic potential. This emerging area examines recent developments of palladium-catalyzed difunctionalization reactions, with a focus on mechanistic strategies that allow for functionalization of a common palladium alkyl intermediate.
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