Issue 2, 1990
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Novel reaction of uracil derivatives possessing electron-withdrawing groups at the 5-position with amines: exchange reaction between the N1-portion of uracils and amines

Kosaku Hirota,   Yukio Kitade,   Hironao Sajiki,   Yoshifumi Maki  and  Motoi Yogo  

Abstract

The reaction of 1,3-disubstituted uracils possessing an electron-withdrawing group such as nitro, carbamoyl, and cyano at the 5-position with primary amines resulted in the exchange of the N1-portion of the uracil ring with the amine moiety. The exchange reactions were influenced by the nature of substituents at the 5- and N1-position. The reaction sequence is explained in terms of addition, ring-opening, and ring-closure.

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/P19900000367
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1990, 367-373

Permissions

Request permissions

Novel reaction of uracil derivatives possessing electron-withdrawing groups at the 5-position with amines: exchange reaction between the N1-portion of uracils and amines

K. Hirota, Y. Kitade, H. Sajiki, Y. Maki and M. Yogo, J. Chem. Soc., Perkin Trans. 1, 1990, 367 DOI: 10.1039/P19900000367

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements