Issue 23, 2008
From the journal:

Chemical Communications

Isolation of calcium phosphate crystals from complex biological fluids using bisphosphonate-modified superparamagnetic beads†

Aaron Hernandez-Santana,a   Alexander Yavorskyy,a   Adedayo Olinyole,a   Geraldine M. McCarthyb  and  Gillian P. McMahon*a  

* Corresponding authors

a Bioanalytical Chemistry & Diagnostics Group, National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Ireland
E-mail: gillian.mcmahon@dcu.ie
Fax: (+353) 1700 5503
Tel: (+353) 1700 5914

b Mater Misericordiae University Hospital, Ireland

Abstract

The surface of superparamagnetic magnetic beads was modified with bisphosphonates to selectively capture calcium phosphate crystals from complex biological fluids (i.e. synovial fluid).

Graphical abstract: Isolation of calcium phosphate crystals from complex biological fluids using bisphosphonate-modified superparamagnetic beads

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Article information

DOI
https://doi.org/10.1039/B801750F
Article type
Communication
Submitted
31 Jan 2008
Accepted
17 Apr 2008
First published
08 May 2008

Chem. Commun., 2008, 2686-2688

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Isolation of calcium phosphate crystals from complex biological fluids using bisphosphonate-modified superparamagnetic beads

A. Hernandez-Santana, A. Yavorskyy, A. Olinyole, G. M. McCarthy and G. P. McMahon, Chem. Commun., 2008, 2686 DOI: 10.1039/B801750F

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