Issue 15, 2004
From the journal:

Chemical Communications

A Suzuki–Miyaura coupling mediated deprotection as key to the synthesis of a fully lipidated malarial GPI disaccharide†

Xinyu Liua  and  Peter H. Seeberger*a  

* Corresponding authors

a Laboratorium für Organische Chemie, ETH Zürich, 8093 Zürich, Switzerland
E-mail: seeberger@org.chem.ethz.ch
Fax: +41-1-633-1235

Abstract

Ligandless palladium-catalyzed Suzuki–Miyaura coupling converted an inert p-bromobenzyl ether to a DDQ-labile p-(3,4-dimethoxyphenyl) benzyl ether in the presence of azide functionality and this strategy serves as a key step for the convergent synthesis of a fully lipidated malaria GPI disaccharide.

Graphical abstract: A Suzuki–Miyaura coupling mediated deprotection as key to the synthesis of a fully lipidated malarial GPI disaccharide

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Article information

DOI
https://doi.org/10.1039/B407324J
Article type
Communication
Submitted
14 May 2004
Accepted
09 Jun 2004
First published
09 Jul 2004

Chem. Commun., 2004, 1708-1709

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A Suzuki–Miyaura coupling mediated deprotection as key to the synthesis of a fully lipidated malarial GPI disaccharide

X. Liu and P. H. Seeberger, Chem. Commun., 2004, 1708 DOI: 10.1039/B407324J

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