Issue 12, 2008
From the journal:

Chemical Society Reviews

Recent progress in the total synthesis of naphthyridinomycin and lemonomycin tetrahydroisoquinoline antitumor antibiotics (TAAs)

Peter Siengalewicz,a   Uwe Rinnera  and  Johann Mulzer*a  

* Corresponding authors

a Department of Organic Chemistry, University of Vienna, Währingerstrasse 38, Austria
E-mail: peter.siengalewicz@univie.ac.at, uwe.rinner@univie.ac.at, johann.mulzer@univie.ac.at
Fax: +43 1 4277 52189
Tel: +43 1 4277 52190

Abstract

In this tutorial review, which should be of general interest to synthetic organic chemists at large, recent progress in the total synthesis of the tetrahydroisoquinoline antitumor antibiotics cyanocycline A, naphthyridinomycin, bioxalomycin α2, and lemonomycin is highlighted in detail and some biological background information is given as well. Preparations of truncated derivatives and uncompleted synthetic approaches are also described. The literature coverage includes the newest research results through the year 2008.

Graphical abstract: Recent progress in the total synthesis of naphthyridinomycin and lemonomycin tetrahydroisoquinoline antitumor antibiotics (TAAs)

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B804167A
Article type
Tutorial Review
Submitted
13 Jun 2008
First published
14 Oct 2008

Chem. Soc. Rev., 2008,37, 2676-2690

Permissions

Request permissions

Recent progress in the total synthesis of naphthyridinomycin and lemonomycin tetrahydroisoquinoline antitumor antibiotics (TAAs)

P. Siengalewicz, U. Rinner and J. Mulzer, Chem. Soc. Rev., 2008, 37, 2676 DOI: 10.1039/B804167A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements