Sol–gel and precursor-derived coatings with cover function on medical alloys

Bettina Hoffmann; Martina Feldmann; Günter Ziegler

doi:10.1039/B707996F

Sol–gel and precursor-derived coatings with cover function on medical alloys†

Bettina Hoffmann,‡*^a Martina Feldmann ‡*^a and Günter Ziegler^a

* Corresponding authors

^a University of Bayreuth, Friedrich-Baur-Research-Institute for Biomaterials, Bayreuth, Germany
E-mail: bettina.hoffmann@fbi-biomaterialien.de, martina.feldmann@fbi-biomaterialien.de
Fax: +49 921 555589
Tel: +49 921 555593

Abstract

Various studies have reported detectable urine and serum levels of metal ions or their accumulation in organs or tissues of patients with metal implants. The concentrations of these ions are considerably higher in the tissue surrounding the implants. These ions may lead to systematic toxicity, carcinogenesis or allergic reactions, and influence the osseointegration and stability of the implants. Developments in the field of orthopaedic implants are in progress which involve covering the metal implants with a layer, which may limit the leakage of metal ions and reduce problems with loosening of the implants. In this study it is shown that sol–gel coatings (TiO₂) and precursor-derived coatings in the system Si–C–N(–Ti) enhance the in vitro cytocompatibility of medically relevant alloys and also hinder the diffusion of toxic ions like vanadium, cobalt and chromium ions out of Ti6Al4V and a cast Co28Cr6Mo alloy, respectively.

This article is part of the themed collection: Biomedical materials

Article information

https://doi.org/10.1039/B707996F

Article type

Paper

Submitted

25 May 2007

Accepted

25 Jul 2007

First published

06 Aug 2007

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J. Mater. Chem., 2007,17, 4034-4040

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Sol–gel and precursor-derived coatings with cover function on medical alloys

B. Hoffmann, M. Feldmann and G. Ziegler, J. Mater. Chem., 2007, 17, 4034 DOI: 10.1039/B707996F

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Journal of Materials Chemistry

Sol–gel and precursor-derived coatings with cover function on medical alloys†

Abstract

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Sol–gel and precursor-derived coatings with cover function on medical alloys

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