Issue 4, 2006
From the journal:

Lab on a Chip

Continuous flow separation of particles within an asymmetric microfluidic device

Xunli Zhang,a   Jon M. Cooper,b   Paul B. Monaghanb  and  Stephen J. Haswell*a  

* Corresponding authors

a Department of Chemistry, The University of Hull, Hull, United Kingdom
E-mail: S.J.Haswell@Hull.ac.uk
Fax: +44 (0) 1482 466410
Tel: +44 (0) 1482 465469

b Department of Electronics and Electrical Engineering, University of Glasgow, Glasgow, United Kingdom

Abstract

A microfluidic based device has been developed for the continuous separation of polymer microspheres, taking advantage of the flow characteristics of systems. The chip consists of an asymmetric cavity with variable channel width which enables continuous amplification of the particle separation for different size particles within the laminar flow profile. The process has been examined by varying the sample inlet position, the sample to media flow rate ratio, and the total flow rate. This technique can be applied for manipulating both microscale biological and colloidal particles within microfluidic systems.

Graphical abstract: Continuous flow separation of particles within an asymmetric microfluidic device

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Article information

DOI
https://doi.org/10.1039/B515272K
Article type
Paper
Submitted
27 Oct 2005
Accepted
02 Mar 2006
First published
13 Mar 2006

Lab Chip, 2006,6, 561-566

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Continuous flow separation of particles within an asymmetric microfluidic device

X. Zhang, J. M. Cooper, P. B. Monaghan and S. J. Haswell, Lab Chip, 2006, 6, 561 DOI: 10.1039/B515272K

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