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Chem. Commun., 2007, 1436 - 1437, DOI: 10.1039/b617926f

Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions

Ernest O. Nwoye and Gregory B. Dudley

2-(4-Methoxybenzyloxy)-4-methylquinoline reacts with methyl triflate in the presence of alcohols to generate a neutral organic salt that transfers the para-methoxybenzyl (PMB) protecting group onto alcohols in high yield and under mild conditions.

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