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Chem. Commun., 2009, 5150 - 5152, DOI: 10.1039/b909766j


One-pot cascade Michael–Michael–Aldol condensation for diastereoselective synthesis of nitro-substituted cyclohexanes

Yunfeng Chen, Cheng Zhong, Xiaohua Sun, Novruz G. Akhmedov, Jeffrey L. Petersen and Xiaodong Shi


A one-pot reaction of nitroalkenes and enones was developed for the preparation of nitro-vinyl-substituted cyclohexanes, which could be simply converted into poly-N-heterocycles.

Graphical abstract image for this article  (ID: b909766j)