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Chem. Commun., 2005, 2101 - 2103, DOI: 10.1039/b418383e

Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection

Jonathan K. Pokorski, Jwa-Min Nam, Rafael A. Vega, Chad A. Mirkin and Daniel H. Appella

trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.

Graphical abstract image for this article (ID: b418383e)