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Chem. Commun., 2006, 1064 - 1066, DOI: 10.1039/b517997a


Glycoconjugates of gadolinium complexes for MRI applications

David A. Fulton, Elisa M. Elemento, Silvio Aime, Linda Chaabane, Mauro Botta and David Parker


Examples of C-4 symmetric, medium MW conjugates incorporating 12 glucose or galactose groups linked via four dendritic wedges to a central Gd complex have been characterised; their enhanced relaxivity is interpreted in terms of effective motional coupling and large contributions from second sphere water molecules.

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