Issue 20, 2009
From the journal:

Chemical Communications

New method to prepare very stable and biocompatible fluorescent silica nanoparticles†

Shin-Woo Ha,a   Corinne E. Camalier,b   George R. Beck Jr.b  and  Jin-Kyu Lee*a  

* Corresponding authors

a Department of Chemistry, Seoul National University, Seoul, Korea
E-mail: jinklee@snu.ac.kr
Fax: +82-2-882-1080
Tel: +82-2-880-8830

b Division of Endocrinology, Metabolism and Lipids, Emory University School of Medicine, Atlanta, GA, USA
E-mail: george.beck@emory.edu
Fax: +1-404-727-1300
Tel: +1-404-727-1340

Abstract

A new synthetic method has been developed to prepare fluorescent silica nanoparticles without employing isothiocyanated dye molecules and (3-aminopropyl)triethoxysilane (APS) for the thiourea linkage formation; the resulting fluorescent silica nanoparticles show excellent photochemical, thermal and pH stabilities and a good biocompatibility with over 85% viability from various cell types.

Graphical abstract: New method to prepare very stable and biocompatible fluorescent silica nanoparticles

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Article information

DOI
https://doi.org/10.1039/B902195G
Article type
Communication
Submitted
02 Feb 2009
Accepted
13 Mar 2009
First published
06 Apr 2009

Chem. Commun., 2009, 2881-2883

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New method to prepare very stable and biocompatible fluorescent silica nanoparticles

S. Ha, C. E. Camalier, G. R. Beck Jr. and J. Lee, Chem. Commun., 2009, 2881 DOI: 10.1039/B902195G

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