Issue 2, 2007

System properties of ErbB receptor signaling for the understanding of cancer progression

Abstract

An intracellular signal transduction network constitutes an assembled machinery to control the dynamics of kinase–phosphatase cascade and gene expression. Spatio-temporal analyses of the cellular process can explain the biochemical role of the receptor tyrosine kinases in cancer development from a system point of view.

Graphical abstract: System properties of ErbB receptor signaling for the understanding of cancer progression

Article information

Article type
Highlight
Submitted
04 Sep 2006
Accepted
20 Nov 2006
First published
18 Dec 2006

Mol. BioSyst., 2007,3, 111-116

System properties of ErbB receptor signaling for the understanding of cancer progression

M. Hatakeyama, Mol. BioSyst., 2007, 3, 111 DOI: 10.1039/B612800A

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