Synthesis of (±)-3-methoxy-6,15-diazaestra-1,3,5,7,9,14-hexaene
Abstract
(±)-3-Methoxy-6,15-diazaestra-1,3,5,7,9,14-hexaene (IX) has been synthesised from 3-methoxy-8-methyl-9,10-dihydrophenanthridin-7(8H)-one (IV)via a modified Curtius rearrangement of the intermediate Michael condensation product (VI).