Issue 5, 1994

Stereospecific binding of chemically modified salen-type Schiff base complexes of copper(II) with DNA [salen = bis(salicyclidene)ethylenediamine]

Abstract

DNA-fibre ESR measurements reveal that the orientation of water-soluble cationic salen-type Schiff base complexes of copper(II) on DNA changes by modification of the bridging group between two imino nitrogens in the complex; the 1,2-phenylenediamine and 2,3-naphthalenediamine bridges enable the complex to intercalate to DNA, while the ethylenediamine bridge induces groove binding.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1994, 625-626

Stereospecific binding of chemically modified salen-type Schiff base complexes of copper(II) with DNA [salen = bis(salicyclidene)ethylenediamine]

K. Sato, M. Chikira, Y. Fujii and A. Komatsu, J. Chem. Soc., Chem. Commun., 1994, 625 DOI: 10.1039/C39940000625

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