Cyclization of compound 5c in trifluoroacetic acid/hexamethylenetetramine produces Tröger's base analogue 6c in 75% yield with 70% diastereoselectivity.
U. Maitra, B. G. Bag, P. Rao and D. Powell, J. Chem. Soc., Perkin Trans. 1, 1995, 2049 DOI: 10.1039/P19950002049
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